284. Evaluation of Oral Step-Down Therapy for Enterobacteriaceae Bloodstream Infection
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چکیده
منابع مشابه
assessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
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15 صفحه اولAcute bacterial osteoarticular infections: eight-year analysis of C-reactive protein for oral step-down therapy.
BACKGROUND One of the most important decisions in the treatment of osteoarticular infections is the time at which parenteral therapy can be changed to oral therapy. C-reactive protein (CRP) is an acute inflammatory indicator with a half-life of 19 hours and thus can be helpful in assessing the adequacy of therapy for bacterial infections. At our institution, a combination of CRP and clinical fi...
متن کاملSupport for higher ciprofloxacin AUC 24/MIC targets in treating Enterobacteriaceae bloodstream infection.
OBJECTIVES Given concerns regarding optimal therapy for serious Gram-negative infections, the goal was to characterize the pharmacodynamics of ciprofloxacin in the context of treating bloodstream infection. PATIENTS AND METHODS Data were collected from the medical records of 178 clinical cases. Blood isolates were retrieved and ciprofloxacin MICs were measured. Forty-two cases in which ciprof...
متن کاملRisk factors for ineffective therapy in patients with bloodstream infection.
BACKGROUND Infections occurring among outpatients having recent contact with the health care system have been termed health care-associated infections. The objective of this study was to analyze the impact of health care-associated status on effectiveness of initial therapy in hospitalized patients with bloodstream infections. METHODS Prospective cohort study of adults with bloodstream infect...
متن کاملMedical therapy for Crohn's disease: top-down or step-up?
The emergency of effective biological therapy in the treatment of Crohn's disease (CD) has led to a clinical debate about 'step-up versus top-down strategy'. Step-up refers to the classic therapeutic approach, namely progressive intensification of treatment as disease severity increases. Top-down refers to the early introduction, in all CD patients, of intensive therapies, including biological ...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2020
ISSN: 2328-8957
DOI: 10.1093/ofid/ofaa439.328